Anne Brunet is a biologist who has made important contributions to our understanding of the molecular mechanisms of aging and longevity.
She developed an original line of investigation to understand aging based on the integration of model organisms with diverse lifespans—worms, fish and mice. Using the worm Caenorhabditis elegans, Brunet and her lab identified pathways involved in delaying aging in response to external stimuli such as availability of nutrients and availability of the opposite sex. She made the exciting discoveries that lifespan extension can be regulated by chromatin modifiers and inherited in a transgenerational epigenetic manner. Her research also uses mouse models to address complex questions about mammalian aging, notably mechanisms regulating neural stem cell aging. Brunet pioneered the naturally short-lived African killifish as a promising new model to identify principles underlying aging and suspended animation.
Organ Synchronization in Aging and Suspended Animation
Wednesday, October 4, 2023 | 18:30 | KUNSTHAUS Zurich, Chipperfield Building